Drug Uses

Carisoprodol is a muscle relaxant used to relieve the pain and stiffness of muscle spasms and discomfort due to strain and sprain.

How Taken

Carisoprodol is taken orally. The usual adult dosage of Carisoprodol is one 350 mg tablet, three times daily and at bedtime. Usage in patients under age 12 is not recommended. It is recommended that you take Carisoprodol with food, or with milk, to minimize the likelihood that you will suffer an upset stomach as a result of taking the medication.

Warnings/Precautions

Do not take Carisoprodol if you have acute intermittent porphyria. Before taking Carisoprodol, tell your doctor if you have kidney or liver disease. You may need a lower dose or special monitoring during your therapy. It is not known whether Carisoprodol will harm an unborn baby. Do not take Carisoprodol without first talking to your doctor if you are pregnant. It is also not known whether Carisoprodol passes into breast milk. Do not take Carisoprodol without first talking to your doctor if you are breast-feeding a baby. Carisoprodol is not approved for use in children younger than 12 years of age.

Missed Dose

If you miss a Carisoprodol dose, take it as soon as remembered if it is within an hour or so. If you do not remember until later, skip the missed dose and resume your usual dosing schedule. Do not 'double-up' the Carisoprodol dose to catch up.

Possible Side Effects

Carisoprodol may cause dizziness, vertigo, ataxia, tremor, agitation, irritability, headache, depressive reactions, syncope, and insomnia. Allergic or idiosyncratic reactions occasionally develop. They are usually seen within the period of the first to fourth dose in patients having had no previous contact with the drug. Skin rash, erythema multiforme, pruritus, eosinophilia, and fixed drug eruption with cross reaction to meprobamate have been reported with Carisoprodol. Severe reactions have been manifested by asthmatic episodes, fever, weakness, dizziness, angioneurotic edema, smarting eyes, hypotension, and anaphylactoid shock.

Storage

Store at controlled room temperature 15°-30°C (59°-86°F). Dispense in a tight container.

Overdose

Seek emergency medical attention. Symptoms of a Carisoprodol overdose include low blood pressure (weakness, fainting, confusion), decreased breathing, and unconsciousness.

More Information

Use caution when driving, operating machinery, or performing other hazardous activities. Carisoprodol may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Carisoprodol.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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General considerations in the use of muscle relaxants
Muscle relaxants are principally used to provide good muscular relaxation for surgery. When they are used respiration must be controlled via an endotracheal tube. A few general guidelines for the use of relaxants are listed below:
1. Always be certain that you will able to ventilate the patient by face mask before paralysing them.
2. If a rapid onset of action is required then suxamethonium should be used as it acts more quickly than any of the non-depolarising drugs. If a short duration of paralysis is required suxamethonium is most suitable and may be given in repeated doses provided atropine is administered prior to the second dose of suxamethonium to avoid bradycardia.
3. Non-depolarising muscle relaxants take about one and a half to two minutes to act and you should allow time for relaxation to develop before attempting intubation.
4. The supplemental dose should be about 25% of the initial dose. Never attempt to reverse the relaxation until at least 15-20 minutes after the last dose of relaxant was given.
5. Never extubate a patient until you are certain that the paralysis has been reversed and they have adequate muscle strength to protect their airway and breathe. One way of testing this is to assess whether they are able to lift their head off the pillow for 5 seconds. Ensure that breathing is of adequate depth and frequency.
6. It takes some time before the larynx is able to protect the airway and so the patient is best placed in the lateral position for recovery.
7. If a nerve stimulator is available it can be used to monitor the degree of relaxation. However it is not essential and relaxants can be safely be used without a nerve stimulator by careful observation of clinical signs.
8. When muscle relxants are administered awareness is always a danger since a paralysed patient cannot move in response to pain. It is therefore essential to ensure that the depth of anaesthesia is adequate.

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